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汪伟
信息来源:麻醉科   发布人:系统管理员   发表时间:2014-08-26 11:45:11   访问次数:
    

第四军医大学口腔医院麻醉科,讲师、主治医师、科室副主任

E-Mail:weiwang@fmmu.edu.cn;free2xavi@yahoo.com

受教育经历

位/时间

单位

专业

本科/2000-2005

第四军医大学

临床医学

硕士/2005-2008

第四军医大学

神经科学

博士/2008—2011

第四军医大学

神经科学

联合培养博士/2010—2011

约翰霍普金斯大学医学院

神经科学

工作经历

时间

单位

职务职称

2011-至今

第四军医大学口腔医院麻醉科

主治医师/讲师

2014-至今

第四军医大学口腔医院麻醉科

副主任

工作专长

1、口腔颌面外科麻醉

2、婴幼儿手术麻醉

3、困难气道处理

科研奖励

1、2008年亚太神经化学组织(APSN)年会“Tokuji Ikenaka”报告金奖    

2、2008年中国解剖学会学术年会最佳论文报告奖

3、2009年国家科技进步一等奖(神经病理性痛模型的创建及其在镇痛机制和治疗研究中的应用)第十四获奖者

4、2011年第四军医大学神经科学精品年会报告金奖

5、2011年亚洲疼痛论坛“Outstanding poster”

6、2011年中国神经科学年会“赛诺菲-安万特”优秀论文奖

7、2011年第四军医大学博士论坛“最佳奖”

8、2013年陕西省“优秀博士学位论文”

承担课题:

1、国家自然科学基金面上项目:组蛋白去乙酰化酶调控星形胶质细胞谷氨酸转运体参与疼痛慢性化的机制研究,81271229,资助额度:70万元,年限:2013-2016

2、陕西省科技统筹创新工程项目:全身麻醉导致儿童神经功能发育异常的防治关键策略及药物研究,资助额度:50万元,年限:2014-2015

3、第四军医大学青年英才资助,资助额度:3万元,年限:2012-2013

4、第四军医大学优秀博士课题资助,资助额度:4万元,年限:2009-2011

论文发表:

1. Feng D,Wang W(cofirst), Dong Y, Wu L, Huang J, Ma Y, Zhang Z, Wu S, Gao G, Qin H. Ceftriaxone alleviates early brain injury after subarachnoid hemorrhage by increasing excitatory amino acid transporter 2 expression via the PI3K/Akt/NF-κB signaling pathway.Neuroscience. 2014;268:21-32.

2. Wang W, Mei XP, Chen L, Tang J, Li JL, Wu SX, Xu LX,Li YQ.Triptolide prevents and attenuates neuropathic pain via inhibiting central immune response.Pain Physician. 2012; 15: E995-E1006.

3. Feng QX, Feng Fan, Feng XY, Zhao QC,Wang W*. Resolvin D1 reverses chronic pancreatitis-induced mechanical allodynia, phosphorylation of NMDA receptors, and cytokines expression in the thoracic spinal dorsal horn. BMC Gastroenterol. 2012; 12:148.

4. Wang W, Mei XP, Wei YY, Zhang MM, Zhang T, Wang W, Xu LX, Wu SX, Li YQ.Neuronal NR2B-containing NMDA receptor mediates spinal astrocytic c-Jun N-terminal kinase activation in a rat model of neuropathic pain.Brain Behav Immun. 2011; 25:1355-1366.

5. Wang W,Petralia RS, Takamiya K, Xia J, Li YQ, HuganirRL, Tao YX, Yaster M. Preserved acute pain and impaired neuropathic pain in mice lacking protein interacting with C kinase 1.Mol Pain. 2011; 7:11.

6.  Wang W, Gu JG, Li YQ, Tao YX. Are voltage-gated sodium channels on dorsal root ganglions involved in the development of neuropathic pain?Mol Pain. 2011; 7:16.

7. Wang W,Atianjoh F, Gauda E, Yaster M, Li YQ, Tao YX. Increased expression of sodium channel subunit Nav1.1 in the injured dorsal root ganglion after peripheral nerve injury.Anat Rec (Hoboken). 2011; 294:1406-1011.

8. Wang W, Wang W, Mei XP, Huang J, Wei YY, Wang YY, Wu SX, Li YQ.Crosstalk between spinal astrocytes and neurons in nerveinjury-induced neuropathic pain.PLoS One. 2009; 4:e6973.

9. Wang W, Wang W, Wang YY, Huang J, Wu SX, Li YQ.Temporal changes of astrocyte activation and glutamate transporter-1 expression in the spinal cord after spinal nerve ligation-induced neuropathic pain.Anat Rec (Hoboken), 2008; 291:513-518.

10. Mei XP,Wang W(cofirst), Wang W, Zhu C, Chen L, Zhang T, Xu LX, Wu SX, Li YQ. Combining ketamine with astrocytic inhibitor as a potential analgesic strategy for neuropathic pain ketamine, astrocytic inhibitor and pain.MolPain. 2010;6:50.

11. Mei XP,Wang W(cofirst), Wang W, Li YM, Zhang H, Wu SX, Li YQ, Xu LX.Inhibiting astrocytic activation: a novel analgesic mechanism of ketamine at the spinal level?J Neurochem.2009; 109:1691-1700.

12. Zhang H,Wang W(cofirst), Gao W, Ge YL, Zhang J, Wu SX, Xu LX.Effect of propofol on the levels of neurotransmitters in normal human brain: A magnetic resonance spectroscopy study,Neurosci Lett. 2009; 467:247-251.

13.Hui R,Wang W(cofirst), Chen T, Lü BC, Li H, Zhang T, Wu SX, Li YQ.Origins of endomorphin-2 immunopositive fibers and terminals in the spinal dorsal horn of the rat.Neuroscience. 2010;169:422-430.

14. Feng QX,Wang W(cofirst), Feng XY, Mei XP, Zhu C, Liu ZC, Li YQ, Dou KF, Zhao QC.Astrocytic activation in thoracic spinal cord contributes to persistent pain in rat model of chronic pancreatitis.Neuroscience. 2010;167:501-509.

15. Zhang H,Wang W(cofirst), Zhao ZJ, Ge YL, Zhang JS, Yu DH, Chai W, Wu SX, Xu LX. The action sites of propofol in the normal human brain revealed by functional magnetic resonance imaging.Anat Rec (Hoboken). 2010; 293:1985-1990.

16. Mei XP, Zhou Y,Wang W(cofirst), Tang J, Wang W, Zhang H, Xu LX, Li YQ. Ketamine depresses toll-like receptor 3 signaling in spinal microglia in a rat model of neuropathic pain.Neurosignals. 2011; 19:44-53.

17. Huang J,Wang W, Chen J, Ge SN,Wei YY,Wang YY,Kaneko T, Li YQ, Wu SX. Neurochemical features of enkephalinergic neurons in the mouse trigeminal subnucleus caudalis.Neurochem Int.2011; 58:44-51.

18. Tong W,Wang W, Huang J, Ren N, Wu SX, Li YQ. Spinal high-mobility group box 1 contributes to mechanical allodynia in a rat model of bone cancer pain.Biochem Biophys Res Commun. 2010; 395:572-576.

19. Mei XP, Zhang H,Wang W, Wei YY, Zhai MZ, Wang W, Xu LX, Li YQ.Inhibition of spinal astrocytic c-Jun N-terminal kinase (JNK) activation correlates with the analgesic effects of ketamine in neuropathic pain.J Neuroinflammation. 2011; 8:6.

20. Huang J, Chen J,Wang W, Wang W, Koshimizu Y, Wei YY, Kaneko T, Li YQ, Wu SX. Neurochemical properties of enkephalinergic neurons in lumbar spinal dorsal horn revealed by preproenkephalin-green fluorescent protein transgenic mice.J Neurochem. 2010; 113:1555-1564.

21. Gao CJ, Li JP,Wang W, Lü BC, Niu L, Zhu C, Wei YY, Zhang T, Wu SX, Chai W, Li YQ.Effects of intracerebroventricular application of the delta opioid receptor agonist dadle on neurological recovery following asphyxial cardiac arrest in rats.Neuroscience.2010; 168:531-542.

22. Liu CR, Duan QZ,Wang W, Wei YY, Zhang H, Li YQ, Wu SX, Xu LX.Effects of intrathecal isoflurane administration on nociception and Fos expression in the rat spinal cord.Eur J Anaesthesiol. 2011; 28:112-119.

23. Han LC, Zhang H,Wang W, Wei YY, Sun XX, Yanagawa Y, Li YQ, Xu LX, Wu SX. The effect of sevoflurane inhalation on gabaergic neurons activation: observation on the GAD67-GFP knock-in mouse.Anat Rec (Hoboken). 2010; 293:2114-22.

24. Zhang H, Mei XP,Wang W, Sun XD.Blocking conversion of GABAergic inhibition as a potential mechanism of propofol-mediated brain protection following resuscitation.Drug News Perspect.2009; 22:525-529.

25. Huang J, Wang YY,Wang W, Li YQ, Tamamaki N, Wu SX.5-HT(3A) receptor subunit is expressed in a subpopulation of GABAergic and enkephalinergic neurons in the mouse dorsal spinal cord.Neurosci Lett. 2008; 441:1-6.

26. Huang J, Wang YY,Wang W, Wei YY, Li YQ, Wu SX.Preproenkephalin mRNA is expressed in a subpopulation of GABAergic neurons in the spinal dorsal horn of the GAD67-GFP knock-in mouse.Anat Rec (Hoboken). 2008; 291:1334-1341.

27. Wu LA, Huang J,Wang W, Li YQ, Wang XJ, Wu SX.Activation of GABAergic neurons following tooth pulp stimulation.J Dent Res. 2010; 89:532-536.

28. Wu LA, Huang J,Wang W, Wang XJ, Wu SX.Down-regulation of K+ -Cl- co-transporter 2 in mouse medullary dorsal horn contributes to the formalin-induced inflammatory orofacial pain.Neurosci Lett.2009; 457:36-40.

29. Lee CY, Perez FM,Wang W,Guan XW, Zhao XL, Sweitzer SM, Raja, TaoYX.Dynamic temporal and spatial regulation of mu opioid receptor expression in the primary afferent neurons following painful peripheral nerve injury.Eur J Pain.2011; 15:669-675.

30. Chen L, Zhu L,Wang K,Wang W,Mei XP,Liu T,Zhang FX,Wang W,Chen T, Li YQ. Antinociceptive effect of prostatic acid phosphatase in a rat model of cancer-induced bone pain. Pain Physician. 2013;16(6):533-546.